Telos Rx wins on pure price if you commit for 6–12 months — $49–$99/mo is unmatched. MadeMed wins on format flexibility with injectable sema, injectable tirz, and oral tirz all available month-to-month. Choose Telos if you know you're in it for the long haul; choose MadeMed if you want to experiment with formats or aren't ready to commit.
Telos Rx and MadeMed represent two fundamentally different approaches to GLP-1 telehealth pricing. Telos uses a commitment model: the longer you commit, the less you pay per month. MadeMed uses an à la carte model: choose your medication format month by month with no long-term obligation.
Neither model is inherently better. The right choice depends on where you are in your GLP-1 journey and how much certainty you have about your treatment path.
| Feature | Telos Rx | MadeMed |
|---|---|---|
| Pricing model | Commitment tiers | À la carte, month-to-month |
| Semaglutide | $49–$199/mo (injectable) | Available (injectable) |
| Tirzepatide | $49–$199/mo (injectable) | Available (injectable + oral) |
| Oral options | Not specified | Oral tirzepatide available |
| 12-month rate | $49/mo | N/A (no commitment discount) |
| 6-month rate | $99/mo | N/A |
| 3-month rate | $129/mo | N/A |
| 1-month rate | $199/mo | See provider |
| Switch molecules | Check with provider | Switch any month |
| Cancellation | Commitment terms apply | Month-to-month, no penalty |
If you've already been on a GLP-1 (with any provider) and you know the medication works for you, Telos Rx's 12-month plan at $49/mo is the lowest verified price in the compounded GLP-1 market. At $588 for a full year of tirzepatide, that's less than what most providers charge for three months.
The commitment model also makes sense if you're switching from a more expensive provider. If you've been paying $299/mo elsewhere and you know you'll continue treatment for at least six months, Telos Rx at $99/mo cuts your annual cost by roughly $2,400.
MadeMed's strength is format flexibility. They offer three distinct product lines through compareglp-1.com: injectable semaglutide, injectable tirzepatide, and oral tirzepatide. You can switch between them month to month without renegotiating your plan.
This matters for patients who:
MadeMed's oral tirzepatide option is particularly notable — few providers offer compounded oral tirzepatide at all, and being able to try it without a commitment makes MadeMed one of the best ways to explore this format.
At what point does Telos Rx's commitment pricing beat MadeMed's flexibility?
If MadeMed's month-to-month pricing is in the $200–$300/mo range (verify directly — pricing varies), then Telos Rx's 12-month plan ($49/mo) saves you $1,800–$3,000 over a year. Even the 6-month plan ($99/mo) saves $600–$1,200 over that period.
The break-even question isn't "is Telos cheaper?" (it almost certainly is on a per-month basis). It's "am I confident enough in my treatment plan to commit for 6–12 months?" If yes, the savings are substantial. If no, MadeMed's flexibility might save you from paying for months of medication you don't end up using.
There's no reason you can't start with one and switch to the other. A common strategy: start with MadeMed to experiment with medication formats (injectable vs. oral, sema vs. tirz). Once you've found what works, lock in a Telos Rx commitment plan at the lower rate for your ongoing treatment.
This two-phase approach gives you the exploration flexibility of MadeMed and the cost efficiency of Telos Rx — without the risk of committing to a year of a medication you haven't tried.
Both are legitimate programs serving different patient needs. Telos Rx is the value play for patients with treatment certainty. MadeMed is the flexibility play for patients still finding their optimal path. The best choice depends on where you are, not which program is "better" in the abstract.
Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting, changing, or stopping any medication. GLP-1 receptor agonists carry risks including thyroid tumors, pancreatitis, and other serious side effects. Individual results vary. Compounded medications are not FDA-approved and carry additional risks.
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